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Tweak, one of Chicago's favorite slang terms!

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(verb) To act stupid and/or crazy

Precious: “Girl, I'm gonna bring like a whole bottle of vodka and orange juice tonight, and have a whole bottle of screwdriver just to myself.”

Selena: “Girl, don't be tweakin' tonight. You gonna throw up all over my bathroom floor.”

“To tweak” has many meanings, including to be high on methamphetamines. Its Chicago reincarnation is used mostly by younger rap fans.

R.Kelly wants to know, “Is I’m tweakin’/how did your sex make me feel this way?” in “Sex Weed” 

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